AI-Built Drug Goes To Clinical Trials

Could the future of medicine be written by artificial intelligence? The first entirely AI-generated drug enters human trials, opening a new chapter in healthcare.

AI-Built Drug Goes To Clinical Trials


  • First-ever completely AI-designed drug, created by biotech startup Insilico Medicine, commences human clinical trials.
  • The drug is a potential treatment for idiopathic pulmonary fibrosis (IPF), a lethal, chronic lung disease.


Insilico Medicine, a biotech startup from Hong Kong, has innovated in healthcare by generating the first-ever drug entirely designed by artificial intelligence. The drug, INS018_055, is now entering Phase II of human clinical trials. The drug aims to treat idiopathic pulmonary fibrosis, a dangerous lung disease that currently affects roughly 100,000 people in the U.S.

Key Facts:

  • Insilico Medicine has over $400 million in funding and is focused on leveraging AI in drug discovery and design.
  • The drug INS018_055 was developed as a potential treatment for idiopathic pulmonary fibrosis (IPF), a chronic lung disease.
  • The discovery process for INS018_055 started in 2020, aiming to overcome limitations with existing treatments.
  • The company also has two other AI-based drugs in the clinical stage, one for Covid-19 and another for cancer treatment.
  • The Phase II trial for INS018_055 is currently taking place in China, with plans to extend the trial to the U.S.


  • AI could redefine how drugs are discovered and designed, expediting the process and addressing less understood or rare diseases.
  • If successful, this trial could validate the use of AI in drug discovery, ushering a new era in the pharmaceutical industry.
  • AI-based drug discovery could potentially minimize side-effects by creating more precise drugs.

Our Take:

  • While the use of AI in drug discovery is exciting, the technology is still relatively new, and it is too early to fully understand its potential and limitations.
  • Finding an effective treatment for IPF is critical, but the high mortality rate associated with the disease suggests that thorough clinical trials are essential to ensure the drug is safe and effective.
  • Insilico Medicine's use of AI in drug discovery is an important leap forward in harnessing technology to combat challenging diseases.
  • Even though AI technology in pharmaceuticals is new, the process and rigour of clinical trials remain the same, ensuring patient safety and efficacy of the drug.


  • AI's potential in pharmaceuticals is being tested as the first fully AI-designed drug begins clinical trials.
  • This advancement could mark a significant shift in drug discovery, bringing new hope for the treatment of less understood or rare diseases.
  • The outcomes of these trials could greatly impact the future of pharmaceuticals, potentially validating AI as a reliable tool in drug discovery and design.


The first fully A.I.-generated drug enters clinical trials in human patients
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